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Confirm low cobalamin (and folate/MMA) before and during therapy

Nat Commun 16 , 3748 (2025)

Leaky gut, or intestinal permeability, happens when the tight junctions in the intestinal lining loosen and allow toxins, pathogens, and undigested food particles to escape into the bloodstream, which can trigger inflammation

Some forms of BPC-157 may also be available in oral or topical formulations, though injections are more commonly used for their direct and potent effects

If a timepoint for blood collection of 1 h post ingestion is selected, the FITC-Dextran assay will represent small intestinal permeability, whilst longer timepoints (46 h) will represent whole gut permeability